like, beyond what any other medication i’ve tried has. It also seemed to help with motivation, slowing my. Creatine or arginine is most popular. Agmatine, decarboxylated arginine, was shown in preclinical studies to exert efficacious neuroprotection by interacting with multiple molecular targets. Venom contains 100mg of DMAA and it is dosed quite high here. Agmatine treatment also attenuates motor function deficits and tissue damage after traumatic brain or spinal cord injuries in animal models 78, 82, 83, 84. Agmatine evoked acute itch in mice. Op · 1y. · 1y. This is important as dietary protein will compete with the absorption. Flavor. But I personally experienced tolerance eventually. This means athletes can use it without any concerns. 5g Betaine Anhydrous 508mg AmealPeptide® No Banned Substances, Soy, or. Mandated by, and serving as a key component of, the Code, the Prohibited List is one of the most important parts of harmonization globally across the anti-doping. Agmatine is available as an oral supplement in powder form known as agmatine sulfate, which is effective at increasing agmatine levels in the body . level 2. Kratom isn't this evil drug or whatever shit their pushing to ban it. We don't have too many of this kind of substances around here, for example of all racetams we only have piracetam and pramiracetam, and I guess that's because we still have to catch up to the western world in terms of psychology/psychiatry due to them being. You can find military-banned supplements list for 2023 below. I've been suffering from phenibut addiction for half a year now. Moreover, agmatine exhibits an effect on imidazoline receptors, calcium channel inhibition and NMDA receptor activity. Agmatine is an intermediate in the biosynthesis of the polyamines putrescine and spermine. This allows more blood to flow into our muscles during a workout, giving us a full feeling in our muscles which can greatly help boost our workouts. This in turn can effect blood pressure - vasodilation can drop blood pressure by some measure. Many people reported great success with Agmatine and even reduction and relief of their depression or anxiety. The Medicines for Human Use (Kava-kava) (Prohibition) Order 2002 SI 3170. Extreme benefits 3 weeks in! 1g in the morning, 500mg at night. What has been banned in the United States are the active alkaloid compounds found within the Ephedra plant, ephedrine and. 500-1000mg of agmatine. Personally, the most I noticed from agmatine was that I became more sensitive to caffeine. Read reviews, learn uses and benefits. Carbohydrates: 5. Introduction. This thread is archived. 21 · Identification number(s) · EC number: 219-617-3 4 First-aid measures · Description of first aid measures · After inhalation: In case of unconsciousness place patient stably in side position for transportation. It has been over 9 months since I began using 1g Agmatine Sulfate in the morning, and 1g in the early evening. It can also be neurotoxic, so use NAC at bedtime, too, just in case. 1. Agmatine sulfate is a decarboxylated metabolite of the amino acid L-arginine. In mammalian brain, agmatine is an endogenous neurotransmitter and/or neuromodulator, which is considered as an endogenous ligand for imidazoline receptors. 3) Agmatine Sulfate Supplementation. 02) aspects of the pain. I guess it’s banned in the EU. I used it to get off methadone for the last year or more, you can take it for years. Increased nitric oxide results in vasodilation, which increases blood flow, nutrient delivery to skeletal muscle, and oxygen transport. I usually spend the day with constant thoughts in my head either distressing or just random phrases/ songs I enjoy. It should be noted that while stand-alone agmatine sulfate products are popular, agmatine is also found in pre-workout and nootropic supplement blends, as well. Core Tip: One of the main challenges in the advancement of antidepressant therapy is the establishment of safe and effective fast-acting antidepressants. Clinical follow-up consists of periodic physical examinations and laboratory blood and urine analyses. Dependence to diazepam can be manifested by withdrawal syndrome which may include symptoms such as irritability, psychosis, sleep disturbance, seizures, mood disturbance, and anxiety. Advanced Search. Details. , shampoo, toothpaste, shaving foam, body washes and facial cleansers). Agmatine Sulfate. Agmatine is supposed to be great for brain health which makes sense. They must also ensure that restricted ingredients are. This makes agmatine sulfate a popular pump-inducing ingredient, but further research is needed on this ingredient (21,22). Then I became a wizard. Energy: 934kJ/223kcal. Agmatine also blocks tolerance to the δ-opioid receptor ligand [d-Pen2,d-Pen5]enkephalin given intrathecally,. 12 Agmatine reduces infarct area in a mouse model of. Both doses of agmatine administered 60-180 min after NO synthase inhibition L-NAME 40 mg/kg i. While agmatine sulfate appears to be generally safe, there. One finger tattoo or ring tattoo per hand is also allowed, provided they don’t exceed the length of the finger from the first to the second knuckle. Identification Generic Name Agmatine DrugBank Accession Number DB08838 Background. Agmatine is effective tolerance reducer, but I’m sure you have heard it can mute the mood lift and euphoria, while increasing the pain relief. Agmatine Sulfate can be found in various pre-workouts and “pump” products, where it serves the purposes of enhancing nitric oxide levels. Dlpa helps you produce dopamine naturally, it makes the detox smoother, you'll still be sick but mentally the boost helps. The results suggest that dietary agmatine sulfate has a significant effect in reducing neuropathic pain intensity associated with painful SFN resistant to treatment. Safety of. It is banned. 01-50mg/kg, although a failure noted elsewhere), SSRIs (5-10mg/kg agmatine injections, dependent on imidazoline receptors), and oddly. 9% physiological saline with a drop of acetic acid and administered 10 min before the. The most scientifically valid claim related to agmatine sulfate is that it can reduce pain. It is not recommended to exceed a daily serving size of 2400 mg (2. It 100% improved symptoms of my depression over the course of several weeks. It quickly became popular for its similarities to banned substances such as Ephedrine, DMAA, and AMP-Citrate. That's just because that was the effect tested for in the study. NFL NBA Megan Anderson Atlanta Hawks Los Angeles Lakers Boston Celtics Arsenal F. I think the results will really depend on your own brain chemistry. $2350 ($1. 07. 67 g/day agmatine sulfate (AgmaSet ® capsules containing G-Agmatine ® brand of agmatine sulfate) for a period of 2 months. Structure Search. I went into it with a positive attitude as well if that means anything. Agmatine in doses of 50, 100. An example of this involves a brand looking to certify a product with Informed Sport that was using a new manufacturing facility. 500 g) and lithium hydroxide (0. Recently I stopped taking it for a couple of days and. Night: Uridine Monophosphate 700mg + Melatonin 300mcg. But for hypotensive people it's a different story. 6g. Agmatine can regulate many critical molecular targets of essential systems in the body. d. BSCG Certified – Banned Substance Free! RAW Nutrition is among one of the few brands that are certified Banned Substances Control Group, or BSCG. Current research suggests it may promote nitric oxide (NO) synthesis better than arginine, as well as aid in proper regulation of cellular energy. I'm undiagnosed but extremely likely to be autistic which is why I came upon this method for treating insomnia (glutamate modulation hypothesis). Agmatine treatment decreased the expression of apoptotic proteins in STZ-icv rats. Best time to take agmatine sulfate. Athletes should be aware of the classes of substances that are on the Prohibited List,. Gorilla Mode Pre-workout Cost. p. While agmatine sulfate appears to be generally safe, there. 3hr 3mins of deep sleep making of 34% of my sleep. Agmatine Sulfate (as Agmass™) is naturally produced in our bodies and is very important with reducing pain, lowering. Prášok. Haloperidol was dissolved in 0. That’s dope. i. 98/Ounce) +. 4 to 3 grams a day over 2 months. Cart. I started taking agmatine for its supposed kratom boosting effects which seem to be minimal. level 2. It is often used in pre-workout supplements. 📒 Show Notes 📒 I hope you enjoy! "Agmatine Sulfate - My Experience and Review (Updated 2021)"📕 FREE EBOOK - 87+ Ways To Increase Dopamine agmatine sulfate powders or pills generally contain 250-750 mg agmatine sulfate per serving where daily intake can be up to 7500 mg/day. Sep 21, 2014 #19 Agmatine is great. Agmatine, however seems different (in terms of legit research data) also it has positive effects on neuropathy/spine injuries. Several studies have shown that Agmatine sulfate may help regulate eNOS production, in return increasing nitric oxide levels in muscle tissue. You can use either I guess but studies have been done on. C) Ethanol intake (g/kg) for male mice that received pretreatment with different doses of agmatine during Test Cycle 4 (second cycle of treatment) (N = 11–12/group). It helps with addiction by tamping down dopamine responses and causing more neuron growth. While many studies point out that Agmatine reduces NOS, it appears to be a regulator rather than something that acutely lowers or increases concentrations. Product Name Agmatine sulfate Cat No. Image: wikimedia. so i originally bought agmatine as a supplement to try and curb my benzo tolerance, after the first couple days of using it i realized it was really really helping my chronic pain from lupus. 99 - $19. The 9 Best Pump Supplements. Puya Yazdi, MD | Written by Joe Cohen, BS | Last updated: August 15, 2023 Agmatine is a compound naturally produced within the body that plays a key role in a. Ketamine is a prototype for rapid-onset antidepressant responses. Agmatine regrows these dead cells and restores our ability to be rational and thus prevent anxiety. Arginine supplementation would have the opposite effect, the two substances collide. Agmatine makes a great pre-workout supplement because it is frequently used to treat depression, nerve pain, and to enhance. ) alone and in combination with NO modulators like L-NAME (15mg/kg, i. Awards 3. This makes agmatine sulfate a popular pump-inducing ingredient, but further research is necessary. Online: $49. One participant of the 3rd cohort (3. e. The drugs used in the present study were morphine sulfate (Temad Pharmaceutical, Tehran, Iran), agmatine sulfate, RX821002, UK 14 304 (Sigma, Germany), and yohimbine (Sigma, UK). Agmatine Evidence Summary Agmatine is a supplement that can modulate many neurotransmitter systems and may be useful for Alzheimer’s and other age-related disease, but there is little human data on its use. US EN. It is a salt form of agmatine discovered back in the early 1900s. Agmatine didn't help me out as far as withdrawals or tolerance taking 2. Honestly it gives me a sort of a blood rush feeling, slight energy boost, and makes me feel like I've had a couple of beers. 5 grams 3 times a day (powder. , including. I usually spend the day with constant thoughts in my head either distressing or just random phrases/ songs I enjoy. This message is automatically added to every post. l-theanine is definitely bad before sleep, it's a slight stimulant, surprising you were able to sleep, sounds like agmatine counteracts l-theanine anti sleep effects. 1 až 3 odmerky (500-1500mg) agmatine sulfate 20-30 min. et al. FitOne or Fit1, can't recall right now, do sell agmatine. 1,500mg of Glucosamine and 1,500mg of Chondroitin sulfate (15). Cardazol was created by ‘Banned Nutrition’ to provide athletes and gym rats with a pre-workout supplement that actually delivers what it promises. 2. And if you take a lot of amino acids, they'll be competing for absorption, so maybe keep that in mind on your journey. The registration samples provided tested positive for high levels of Methylhexanamine, a banned stimulant. Glutamate is good for thinking and learning, but in excess, it causes anxiety and ruminating thoughts that feel loud while we try to sleep. This means it can have tremendous benefits combating the worst diseases from addiction, to cancer, to Alzheimer's and more. Never tried it to try and save money or use less CBD as agmatine is pretty expensive on its own. I tried selegiline but to no avail, it only aggravated my anxiety and worsened my internet addiction. · After skin contact: Immediately wash with water and soap and rinse. What are the benefits of taking Venom?I've read multiple reports that Agmatine Sulfate can drastically improve sleep onset and in general, better overall sleep quality. I read many studies about Agmatine and these. Cucinello-Ragland and Edwards, 2021. Agmatine peptides play a significant role in the therapeutic design. Stressed mice have also shown a significant high serum corticosterone. Agmatine interacts with NMDA and Nitric Oxide neuroreceptors which augments memory and learning ability. While many studies point out that Agmatine reduces NOS, it. The drugs used in the present study were morphine sulfate (Temad Pharmaceutical, Tehran, Iran), agmatine sulfate, RX821002, UK 14 304 (Sigma, Germany), and yohimbine (Sigma, UK). Creatine or arginine is most popular. My experience with agmatine is that dosage and frequency of dosage is very important. I stopped thinking about frequently killing myself, stopped going down negative thought pattern spirals, and I can actually enjoy video games for once. Agmatine sulfate banned – (Image Source: Pixabay. Pylori a microbe known to impact mood and depression negatively. 1). It is also linked to boosting the immunity system. 88. Agmatine sulfate is a compound that is a metabolite of Agmatine, a substance formed by processing arginine. Beginner's Guide • Vendor Warnings • Research Index • Rules. Does Mr Hyde pre workout have creatine? About this item. 1 more reply. All prohibited substances in this class are Specified Substances. Agmatine sulfate has been studied for its potential to improve cognitive function, reduce anxiety and depression, and provide pain relief. Evidence for oral agmatine sulfate safety--a 95-day high dosage pilot study with rats. I don't think agmatine feeds it, I have never read that before, but it does create gastrointestinal problems when you take agmatine and you have H. Fat: 3. But I only use it one day per week to save money, and only in one 750mg dose at that. User accepts all risks, liabilities, and consequences in regards to testing. A. In a randomized, double-blind, placebo-controlled trial of agmatine sulfate (1. I just looked into this, and we've really not had any issues shipping Agmatine Sulfate to the UK. CryptoAgmatine with amphetamines. Most effective dosage for me is 1 gram morning, 1 after work. Note. CAS 2482-00-0. Improves intra-workout energy. ago. But the plaque risk with bromantane is way overblown. Sports. However, it is always advisable to familiarize yourself with the latest. 240 lbs - 175 to 698 mg per day. Bars represented the relative protein quantification of active cleaved caspase-3 on the basis of. In this review, studies demonstrating the antidepressant effects of agmatine are presented and discussed, as well as, the mechanisms of action related to these effects. 373K subscribers in the Nootropics community. Agmatine Sulfate – 1. Agmatine, decarboxylated arginine, exerts beneficial effects in various experimental disease models. Agmatine sulfate has been studied across a range of doses in both animals and humans between 1,250-7,500mg/day. drugs under pre-clinical or clinical development or discontinued, designer drugs,. 67 g agmatine sulfate was encapsulated in gelatin capsules; the regimen consists of six capsules daily, each containing 445 mg, three in the morning and three in the evening after meals. As in all cases of contamination, LGC began the investigation process with the brand and manufacturer. 5g night empty stomach. NCATS GSRS Full Record. It can help to improve blood flow, increase muscle pumps, and reduce muscle fatigue. The recent rediscovery of agmatine as an endogenous ligand for α2-adrenergic and imidazoline receptors in the mammalian brain suggests that this. Malta has warned against using a MusclePharm workout supplement endorsed by Arnold Schwarzenegger following an investigation into its agmatine sulphate content concerning a total of 30 countries. Neuroprotective Benefit: Agmatine has some effects in preclinical rodent models of neurodegenerative disease, but human data. Agmatine was delivered a minimum of 12 hours prior to sensory testing, suggesting that the impact of agmatine in this paradigm is likely due to inhibition. According to several reports and studies, agmatine naturally reverses pain from factors like inflammation, neuropathy and spinal cord injury. Agmatine puts me to sleep and has had no positive effect on confidence/motivation. or s. After 28 days of treatment, animals were humanly. o. Meta Analysis [2018] Increase deep sleep and growth hormone through heat exposure: saunas and hot baths boost slow-wave sleep, while saunas have been shown to elevate growth hormone levels up to 16-fold. The results indicate that agmatine treatment should continue for as long as symptoms persist and corroborate previous observations [22,23] showing that dietary agmatine sulfate treatment lacks any significant side effects. 1g agmatine just as a safety protocol with bromantane. Based on this evidence, we conducted an open-label. I'm not a fan of taking something chronically, so I off-cycle it. Structurally, Agmatine Sulfate is a polycation at physiological pH, possessing four potential hydrogen acceptor groups and three potential. The commodification of the botanical Mitragyna speciosa as kratom products in the United States (US), and their increased availability to consumers, has contributed to a rise in use among a diverse population with myriad substance use histories (Covvey et al. New to this sub. Pylori. Please give this substance a try. Agmatine Sulfate 1000 mg Citrulline Malate 5000 mg Glycerol Monostearate 2000 mg Norvaline 250 mg No2 Vasodilation Support Matrix: Proprietary Blend L-Alpha-Glycerylphosphorylcholine, Vitamin C (As Ascorbic Acid), Rutaecarpine, Epimedium (20%) 500 mg. Acetyl-L-Carnitine offers comparable effect to standard antidepressants with fewer adverse effects. found out it does this potentiation by agmatine's actions on the NMDAR system and neuronal cell structures too (also attributed to increase BDNF factor and neurogenesis). As stated before, agmatine seems to be protective of the gut possibly by reducing intestinal permeability. 6 to 6. Agmatine Sulfate: Following Beta Alanine, we have about 750 milligrams of Agmatine Sulfate. A. 5 oz) at Amazon. It‘s. Agmatine, also known as guanidine, is a metabolite of the conditionally essential amino acid L-arginine. Previous clinical studies strongly support the use of dietary agmatine as a safe and effective treatment for neuropathic pain. 270 Da. Agmatine sulfate may help boost your mood. 1000mg to 1500mg is a common dosage found in pre. I was having drowsy spells and binge eating at 2. While frequently on sale, Gorilla Mode’s baseline price is $49. This serious compound comes from the branched-chain amino acid L-arginine. Clinical trials indicate the safety and effectiveness of short-term (up to 21 days) high dose regimens of oral agmatine sulfate, but longer term studies are lacking. Giggling during disassociation, whether induced by drugs, mediation. In turn, this improves blood flow to the brain. Sodium sulfate: The therapeutic. It may also have anti-inflammatory and neuroprotective effects. Abstract There is presently a great interest in the therapeutic potential of agmatine, decarboxylated arginine, for various diseases. Agmatine sulfate Grape seed extract Caffeine: 20 min prior to exercise: Maximum Bodyweight Exercise Repetitions Completed during a 20-min Exercise Bout: ↑ Repetitions Completed (d = 0. Functions of Agmatine Sulfate: It's this: Bromantane 100-200mg + L-Tyrosine 3g + California Poppy 1-2g + Coffee 1-2 cups + Agmatine Sulfate 2g/ day + Multivitamin. 14. When i started taking agmatine my level of agony went from a 10 to a 4. Agmatine sulfate potentiation question . Now 25% Off. Agmatine long-term safety: Long-term (5 years), high daily dosage of dietary agmatine--evidence of safety: a case report. Interestingly, agmatine was found to ubiquitously exist naturally in plants, animals, and some other foodstuff. NSFW Agmatine banned in Europe? I‘m driving from Germany to UK in a few days and was wondering if I can bring Agmatine with me? I can‘t find certain answers on this. It seems to also provide protection to the cannabinoid receptors relating to tolerance. It's not technically ilegal but it's not stocked by many EU vendors. 1. Up next is the best Agmatine Sulfate. 500mg agmatine sulphate taken half an hour before kratom intake helps with tapering. 6 grams of Agmatine sulfate each day for five years and had no adverse events. Agmatine is the next generation arginine and is often referred to as "Super Arginine" because of its ability to give explosive increases in Nitric Oxide synthesis. Sulfates contain one sulfur atom surrounded by 4 oxygen atoms. These studies have ushered in the use of dietary agmatine as a nutraceutical. 0, and 0. The detailed categorization of neuropathic pain characteristics show significant decrease in burning (p=0. I'm not a fan of taking something chronically, so I off-cycle it. And it has effects on the nervous system, it can help heal traumatic brain injuries and damages from drug use. Agmatine is an endogenous polyamine synthesized by the enzyme arginine decarboxylase. Agmatine binds with high affinity to α2-adrenergic receptors. Participants diagnosed with painful SFN and autonomic dysfunctions were treated with 2. 560 g/day for 10 days, and 3. pre-workout supplements) Contains banned substances Regulating Pain Perception. Agmatine sulfate salt has been used: to study its effects on nod-like receptor protein 3 (NLRP3) inflammasome activation and cytokine responses in sub-chronic restraint stress rat models; as an N-methyl-D-aspartate (NMDA) receptor blocker to study its therapeutic effects on autistic behaviors in the valproic acid-induced animal model of autism;1g Agmatine Sulfate Reply. I'm down to 2x1,5g (kratom) daily and found agmatine helpful getting this low…. View Profile View Forum Posts Registered User Join Date: May 2008 Location: Pennsylvania, United StatesThe neuroprotective effects of agmatine were shown in a mouse 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) model of Parkinson’s disease 51,52 and in cultured cerebellar granule cells and hippocampal cells submitted to glutamate and/or NMDA-induced neurotoxicity 53,54 and corticosterone. May Protect the Brain; Research has shown that agmatine supplementation may protect brain cells from damage. L-citrulline, L-ornithine, and agmatine are the metabolites of L-arginine by nitric oxide synthase (NOS), arginase, and arginine decarboxylase (ADC), respectively. d. 5g. Learn how agmatine can enhance the effects of adderall, reduce depression and anxiety, and improve mood and cognition. 2016: 12 resistance-trained male NCAA Division III football players: Randomized, Double-blind, placebo-controlled, crossover design. Sam Harris' talks on meditation and his app are great. The UK 14 304 was. New comments cannot be posted and votes cannot be cast. 3 In short, agmatine sulfate, as an endogenous neuromodulator and when taken in supplemental form, increases the activity of neurons associated with the handling of stress, anxiety and. Taking 3-3. Contains Beta-Alanine and Agmatine Sulfate; 168 Reviews. Agmatine Sulfate. ) and l-arginine (400mg/kg i. You can use either I guess but studies have been done on. Buy Agmatine Sulfate Powder - Nootropics Depot is the #1 most trusted source for high quality Agmatine Sulfate Powder. Agmatine supplements (e. Yes because it has a half-life in spinal cord/brain of 12 hours. 1. Horbaach's Agmatine Sulfate Supplement: We test our nutrients to ensure purity, potency and excellence. This makes a single serving or scoop (15. It is a bacteria that is present in the gut of 50-75% of the world population. I am a bot, and this action was performed automatically. Depression much better. v. Agmatine sulfate is really cheap and easily obtained. at bedtime also helps boost agmatine's calming effects at night. I usually take the agmatine about 20-30 minutes before the kratom, always first dose sometimes my later doses are closer. But I only use it one day per week to save money, and only in one 750mg dose at that. i havent tried to lose weight as im fairly lean, but i notice agmatine increased performance a bit in the gym. As a result of this compound’s unique storage mechanism, Agmatine Sulfate possesses actions and abilities that its. Normally I feel highly stimulated but. 5g Agmatine Sulfate, 1g Ariginine Nitrate, 1g Beet Root Powder, 500mg Choline Bitartrate, 250mg L-Norvaline, 25mg Sceletium Tortuosum Extract, 15mg Grains Of Paradise. Moreover, agmatine sulfate inhibits the nicotinic receptor and prevents symptoms of narcotic craving. Agmatine is a member of biogenic amines and is an important medicine which is widely used to regulate body balance and neuroprotective effects. And yes, ceasing agmatine alone improved my mood significantly so I can attribute it to agmatine. com) Why is agmatine in pre-workout supplements? Agmatine increases nitric oxide and, in turn, the “pump”. Agmatine, an endogenous guanidine amine, has been shown to produce antidepressant-like effects in animal studies. 089218 Da. Agmatine is one of them. Agmatine experience. Now this is also good for the cardiovascular system as. Rules reminder: Don't promote reckless behavior. The interaction between agmatine and arginine in regards to blood vessels (and 'the pump' for physical exercise) is not clear. The research is still minimal. Agmatine sulfate helps with improvements in mental health, clarity, focus, memory, and stress management. Agmatine vs. Philadelphia 76ers Premier League UFC. I've found that I am not noticing the stimulant effects from any of these drugs nearly as much as I usually do. For example, one notable study examined the effects of agmatine against stroke in rats. 6g. Agmatine is a popular supplement in the body building community due to its “pump” effect – essentially increasing Nitric Oxide and blood flow. To develop an antiserum to agmatine, guinea pigs were immunized with a conjugate of agmatine and BTG, and polyvinylidene fluoride transfer membrane was spotted with agmatine sulfate-BTG conjugate. TL/DR at the bottom. One hour after my first 1g dose, I noticed an immediate change in my mentality. However, the mechanism (s) of action, the impact on whole body gene expression and metabolic pathways, and the potential benefits and risks of long term AGM consumption are still a mystery. It has been traditionally used to treat arthritis, but in recent years it has seen use as a supplement for athletic performance enhancement and pain relief. Dependence to diazepam can be manifested by withdrawal. I would take them 3 times a day everyday (that was the plan) Day 1: Sunday June 9th, 2019. – Regulation of cell repair. So you can buy from ebay. Applications Products Services Documents Support. Most effective dosage for me is 1 gram morning, 1 after work. Worked for my brother, so YmMV. Linear Formula: H 2 N(CH 2) 4 NHC(=NH)NH 2 ·H 2. During the treatment interval, only three participants reported mild-to-moderate adverse effects . Thankfully I've always kept my dosing to 2x per week and no more than 1. Yes, in my experience, Agmatine is likely to synergize and and potentiate cannabis (and probably other drugs as well). I also feel as if it's giving me a slight boost to the potency of coffee. Given agmatine's short half life, I'm tempted to try keeping the same overall dose but cutting individual doses in half and doubling the frequency. At present, the industrial production of agmatine mainly depends on the chemical method, but it is often accompanied by problems including cumbersome processes, harsh reaction conditions,. · 1y. 3. google '200 mg of Zen: L-Theanine Boosts. Agmantine is a natural metabolite of the amino acid arginine. Research has found agmatine to be non-toxic when taken appropriately. Multi-ingredient performance supplements (MIPS) may be comprised of ingredients such as BCAAs, creatine, beta-alanine, agmatine sulfate, taurine, creatinol-o-phosphate, and a combination of nitrate-containing compounds purported to enhance both acute performance and long-term neuromuscular adaptations [3-5].